STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LipULipase LipU. (355 aa)    
Predicted Functional Partners:
Cbs
Cystathionine beta-synthase.
  
    0.835
PE_PGRS63
Triacylglycerol lipase Lip.
  
   
 0.792
RN09_1334
Hypothetical protein.
  
  
 0.731
SerA1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  
 0.682
LppF
Lipoprotein LppF.
     
 0.675
LipC
Esterase LipC.
  
   
 0.662
FadA3
Beta-ketoacyl CoA thiolase FadA; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.582
eis
Enhanced intracellular survival protein; Effector that is released into the host cell and affects host immune responses. Acts as an acetyltransferase that acetylates lysine residues of host proteins.
      
 0.559
LipM
Esterase LipM.
  
   
 0.535
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.527
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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