Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_1561ABC transporter ATP-binding protein. (254 aa)    
Predicted Functional Partners:
Tbd2
ABC transporter ATP-binding protein.
  
 0.997
PknB
Serine/threonine-protein kinase PknB.
  
 
 0.917
SucA
Putative 2-oxoglutarate dehydrogenase SUCA (alpha-ketoglutarate dehydrogenase); Multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase.
   
 
 0.899
PknH2
Protein kinase.
  
 
 0.877
RN09_1564
Serine/threonine-protein kinase PknH.
  
 
 0.837
GltB
Glutamate synthase large subunit.
  
 
 0.709
RN09_2500
Two component sensor histidine kinase DosT.
  
  
 0.680
DevS
Two component sensor histidine kinase DevS.
  
  
 0.680
RN09_1500
Tetronasin ABC transporter integral membrane protein.
  
 
 0.664
RN09_1560
Serine/threonine-protein kinase PknH.
  
 
 0.657
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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