Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa)    
Predicted Functional Partners:
ThrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.999
ThrA
Homoserine dehydrogenase; Overlaps another CDS with the same product name.
 
 0.997
RN09_1598
Homoserine dehydrogenase; Overlaps another CDS with the same product name.
  
 
 0.973
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.940
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
    
 0.915
purM
Phosphoribosylformylglycinamidine cyclo-ligase PurM.
 
    
 0.908
argS
arginine--tRNA ligase.
  
    0.875
IlvE
Branched-chain amino acid aminotransferase.
  
 
 0.848
MetC
O-acetylhomoserine sulfhydrylase.
 
  
 0.848
SdaA
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.842
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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