Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
RN09_1920fatty-acid--CoA ligase FadD11. (462 aa)    
Predicted Functional Partners:
RN09_1919
fatty-acid--CoA ligase FadD11.
  
 0.998
PlsB1
Acyltransferase PlsB; Belongs to the GPAT/DAPAT family.
  
  
 0.956
LipQ
Carboxylesterase LipQ.
   
  
 0.762
PPE21
PPE family protein PPE21; Belongs to the mycobacterial PPE family.
       0.575
FadD2
fatty-acid--CoA ligase FadD2.
 
 
  0.558
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
  0.538
RN09_1649
CysO-cysteine peptidase.
    
 0.528
FadD5
fatty-acid--CoA ligase FadD5.
 
 
 
0.521
RN09_0565
Aldehyde dehydrogenase; Overlaps another CDS with the same product name; Belongs to the aldehyde dehydrogenase family.
   
 
 0.518
RN09_1922
Fumarate reductase.
       0.500
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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