Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TesB1acyl-CoA thioesterase TesB. (306 aa)    
Predicted Functional Partners:
TesB2
acyl-CoA thioesterase TesB.
  
  
 
0.920
PykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
    0.880
RN09_1980
Hypothetical protein.
       0.755
RN09_1984
Hypothetical protein.
       0.653
RN09_1983
Hypothetical protein.
       0.630
RN09_1979
Membrane protein.
       0.587
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.565
PlsB2
Glycerol-3-phosphate acyltransferase; Overlaps another CDS with the same product name; Belongs to the GPAT/DAPAT family.
 
  
 0.552
FadB
Fatty oxidation protein FadB.
 
 
 0.536
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
       0.533
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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