Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CydBCytochrome D ubiquinol oxidase subunit II CydB. (346 aa)    
Predicted Functional Partners:
CydA
Cytochrome D ubiquinol oxidase subunit I CydA.
 0.999
CydD
Cytochrome biosyntheisis ABC transporter ATP-binding protein/permease CydD.
 
  
 0.995
CydC
Cytochrome biosyntheisis ATP-bindingprotein/permease CydC.
 
  
 0.990
RN09_1989
Membrane protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
    0.741
NdhA
NADH dehydrogenase NdhA.
 
   
 0.736
RN09_1466
Proline dehydrogenase.
      
 0.680
nuoA
NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
      
 0.661
Icd2
Isocitrate dehydrogenase.
      
 0.655
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
 0.650
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
  
 0.632
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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