Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RN09_1990Adenylyl cyclase. (114 aa)    
Predicted Functional Partners:
RN09_1989
Membrane protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
     0.996
RN09_1991
Adenylate cyclase.
      0.807
GlyS
glycine--tRNA ligase; Overlaps another CDS with the same product name.
      
 0.713
PhoR
Two component system response sensor kinase PhoR.
   
 
 0.612
CydA
Cytochrome D ubiquinol oxidase subunit I CydA.
       0.526
RN09_4491
cAMP receptor protein.
 
 
 0.525
RN09_1228
Acetyltransferase.
 
 
 0.485
RN09_2988
Transmembrane protein.
 
 
 0.483
CydB
Cytochrome D ubiquinol oxidase subunit II CydB.
       0.465
LipJ
Lignin peroxidase LipJ; Overlaps another CDS with the same product name.
  
     0.458
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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