TB15.3 protein (Mycobacterium tuberculosis variant africanum)

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Score

TB15.3

Iron-regulated universal stress protein. (146 aa)

Predicted Functional Partners:

RN09_2006

0.739

ffh

0.731

RN09_4111

0.721

GuaB2

0.721

PknB

0.715

GuaB3

0.710

crgA

0.607

RN09_2005

0.602

RN09_1632

0.568

RN09_1629

0.520

Your Current Organism:

Mycobacterium tuberculosis variant africanum

NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GuaB2	GuaB3	RN09_4173	RN09_4171	Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Oxidoreductase.	0.984
GuaB2	RN09_4111	RN09_4173	RN09_4111	Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Hypothetical protein.	0.738
GuaB2	TB15.3	RN09_4173	RN09_2007	Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Iron-regulated universal stress protein.	0.721
GuaB2	ffh	RN09_4173	RN09_3531	Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.793
GuaB3	GuaB2	RN09_4171	RN09_4173	Oxidoreductase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.984
GuaB3	RN09_4111	RN09_4171	RN09_4111	Oxidoreductase.	Hypothetical protein.	0.721
GuaB3	TB15.3	RN09_4171	RN09_2007	Oxidoreductase.	Iron-regulated universal stress protein.	0.710
GuaB3	ffh	RN09_4171	RN09_3531	Oxidoreductase.	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.749
PknB	RN09_4111	RN09_0022	RN09_4111	Serine/threonine-protein kinase PknB.	Hypothetical protein.	0.959
PknB	TB15.3	RN09_0022	RN09_2007	Serine/threonine-protein kinase PknB.	Iron-regulated universal stress protein.	0.715
PknB	crgA	RN09_0022	RN09_0019	Serine/threonine-protein kinase PknB.	Cell division protein CrgA; Involved in cell division; Belongs to the CrgA family.	0.428
PknB	ffh	RN09_0022	RN09_3531	Serine/threonine-protein kinase PknB.	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.570
RN09_1629	RN09_1632	RN09_1629	RN09_1632	Adenylate cyclase.	Hypothetical protein.	0.480
RN09_1629	TB15.3	RN09_1629	RN09_2007	Adenylate cyclase.	Iron-regulated universal stress protein.	0.520
RN09_1632	RN09_1629	RN09_1632	RN09_1629	Hypothetical protein.	Adenylate cyclase.	0.480
RN09_1632	TB15.3	RN09_1632	RN09_2007	Hypothetical protein.	Iron-regulated universal stress protein.	0.568
RN09_2005	RN09_2006	RN09_2005	RN09_2006	Mannosyltransferase.	Mannosyltransferase.	0.585
RN09_2005	TB15.3	RN09_2005	RN09_2007	Mannosyltransferase.	Iron-regulated universal stress protein.	0.602
RN09_2006	RN09_2005	RN09_2006	RN09_2005	Mannosyltransferase.	Mannosyltransferase.	0.585
RN09_2006	TB15.3	RN09_2006	RN09_2007	Mannosyltransferase.	Iron-regulated universal stress protein.	0.739