Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2114Transcriptional regulator. (259 aa)    
Predicted Functional Partners:
RN09_2110
Hypothetical protein.
 
    0.873
RN09_2112
Hypothetical protein.
 
    0.869
FadB3
3-hydroxybutyryl-CoA dehydrogenase FadB.
  
    0.846
RN09_2113
Hypothetical protein.
 
    0.846
RN09_2115
Hypothetical protein.
       0.782
RN09_0320
Hypothetical protein.
 
  
 0.780
RN09_2108
Oxidoreductase.
 
  
 0.769
RN09_2111
Hypothetical protein.
 
    0.747
RN09_0605
HTH-type transcriptional regulator.
 
  
 0.728
vapC-18
Ribonuclease VapC12; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
      
 0.662
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (20%) [HD]