Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2149ABC transporter ATP-binding protein/permease. (641 aa)    
Predicted Functional Partners:
PknB
Serine/threonine-protein kinase PknB.
  
 
 0.907
SucA
Putative 2-oxoglutarate dehydrogenase SUCA (alpha-ketoglutarate dehydrogenase); Multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase.
   
 
 0.897
RN09_4111
Hypothetical protein.
 
      0.819
RN09_1501
Tetronasin ABC transporter ATP-binding protein.
 
     
0.625
RN09_1318
Hypothetical protein.
  
     0.582
Cut1
Cutinase.
  
 0.574
Cut2
Cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
 0.574
Cut3
Cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
 0.574
RN09_4256
Hypothetical protein.
  
 0.574
Cut5
Putative cutinase.
  
 0.574
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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