Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cyp143Cytochrome P450 Cyp143. (393 aa)    
Predicted Functional Partners:
Cyp139
Cytochrome P450 Cyp139.
  
  
 0.801
RN09_2794
Cytochrome P450 Cyp121.
  
   
 0.778
RN09_2793
Cytochrome P450 Cyp121.
  
   
 0.751
FadE3
fatty-acid--CoA ligase FadD4.
   
 
 0.734
FadE22
acyl-CoA dehydrogenase FadE22.
   
 
 0.734
RN09_0500
Membrane bound polyketide synthase.
  
 0.726
RN09_2045
Polyketide synthase; Overlaps another CDS with the same product name.
  
 0.726
cwsA
Cell wall synthesis protein CwsA; Required for regulated cell division, cell wall synthesis and the maintenance of cell shape; Belongs to the CwsA family.
      
 0.713
RN09_2201
Ferredoxin.
  
  
 0.693
FadE33
acyl-CoA dehydrogenase FadE33.
   
 
 0.686
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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