Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RN09_2265Malate synthase; Overlaps another CDS with the same product name. (179 aa)    
Predicted Functional Partners:
GlcB
Malate synthase; Overlaps another CDS with the same product name.
     0.994
Icl
Isocitrate lyase.
  
  
 0.901
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.816
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.762
Pca
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.644
RN09_2462
Hypothetical protein.
   
 
 0.624
AceAa
Isocitrate lyase AceAa.
  
  
 0.612
AceAb
Isocitrate lyase AceAb; Overlaps another CDS with the same product name.
  
  
 0.612
RN09_2364
Isocitrate lyase AceAb; Overlaps another CDS with the same product name.
  
  
 0.612
GltA2
Citrate synthase 1; Belongs to the citrate synthase family.
   
 
 0.586
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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