Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2272Hypothetical protein. (349 aa)    
Predicted Functional Partners:
RN09_2273
Hypothetical protein.
 
  
0.974
GuaB1
Inosine-5'-monophosphate dehydrogenase.
  
  
 0.747
Gnd1
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.704
RN09_2278
Transcriptional repressor BlaI.
  
  
 0.653
RN09_2909
Transmembrane protein.
 
   
0.600
RN09_2910
Endoribonuclease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.518
PE_PGRS34
Hypothetical protein.
     
 0.504
GuaA
GMP synthase.
     
 0.469
RN09_2318
Hypothetical protein.
     
 0.464
RN09_2276
Sensor-transducer protein BlaR.
  
    0.463
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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