Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (211 aa)    
Predicted Functional Partners:
UreD
Urease accessory protein UreD.
 
 
 0.997
ureC
Urease subunit alpha.
 
 
 0.985
ureB
Urease subunit beta; Belongs to the urease beta subunit family.
 
 
 0.977
ureA
Urease subunit gamma; Belongs to the urease gamma subunit family.
 
 
 0.974
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.974
RN09_2279
Esterase.
       0.784
RN09_3299
Transmembrane protein.
  
     0.580
RN09_3461
Hypothetical protein.
  
 
 0.570
RN09_3462
Hypothetical protein.
  
 
 0.570
RN09_0419
Transcriptional regulator.
  
     0.567
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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