Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
UreDUrease accessory protein UreD. (226 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.997
ureA
Urease subunit gamma; Belongs to the urease gamma subunit family.
  
 
 0.990
ureB
Urease subunit beta; Belongs to the urease beta subunit family.
  
 
 0.990
ureC
Urease subunit alpha.
  
 
 0.976
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.970
RN09_0419
Transcriptional regulator.
 
     0.747
RN09_2279
Esterase.
       0.697
GltB
Glutamate synthase large subunit.
      
 0.684
RN09_0422
Isoniazid inducible protein IniA.
  
     0.659
IniC
iIsoniazid inducible protein IniC.
  
     0.650
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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