Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ModAMolybdate ABC transporter substrate-binding lipoprotein ModA. (261 aa)    
Predicted Functional Partners:
ModB
Molybdenum ABC transporter permease ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.997
ModC
Molybdenum ABC transporter ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
 
  
 0.993
CysT
Sulfate ABC transporter permease CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
 
 
 0.848
CysW
Sulfate ABC transporter permease CysW.
 
   
 0.779
moaA
Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.724
moaC-2
Cyclic pyranopterin monophosphate synthase accessory protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
   
 0.610
RN09_2288
Oxidoreductase.
       0.568
GltB
Glutamate synthase large subunit.
  
  
 0.545
MoaB2
Pterin-4-alpha-carbinolamine dehydratase.
 
   
 0.530
Mog
Molybdopterin biosynthesis protein.
 
   
 0.529
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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