Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AdhAAlcohol dehydrogenase A. (299 aa)    
Predicted Functional Partners:
Adh
Alcohol dehydrogenase.
 
 0.974
AdhB
Alcohol dehydrogenase B.
  
 
0.952
RN09_0184
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
RN09_0565
Aldehyde dehydrogenase; Overlaps another CDS with the same product name; Belongs to the aldehyde dehydrogenase family.
  
 0.924
AldA
Aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family.
  
 0.924
RN09_2092
Methyltransferase.
  
 
 0.907
RN09_3703
NADP-dependent alcohol dehydrogenase.
 
   
 0.906
RN09_4337
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
     
 0.906
dhmA
Haloalkane dehalogenase; Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
    
 0.904
dhmA-2
Haloalkane dehalogenase; Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
    
 0.904
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.