Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2500Two component sensor histidine kinase DosT. (558 aa)    
Predicted Functional Partners:
DevR
Two component transcriptional regulator DevR.
 
 0.996
RN09_2469
Hypothetical protein.
 
  
 0.943
NarL
Nitrate/nitrite response transcriptional regulator NarL.
 
 
 0.895
RN09_0239
Two component transcriptional regulator.
 
 
 0.786
RN09_2501
Universal stress protein.
 
  
 0.779
RN09_2499
Universal stress protein.
 
  
 0.777
PfkB
6-phosphofructokinase PfkB; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.773
RN09_0475
Transcriptional regulator; Overlaps another CDS with the same product name.
 
 
 0.750
RN09_3051
LuxR family transcriptional regulator.
 
 
 0.749
Acg
NAD(P)H nitroreductase acg.
 
  
 0.722
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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