STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CobNCobalamin biosynthesis protein CobN. (1053 aa)    
Predicted Functional Partners:
CobO
cob(I)alamin adenosyltransferase.
 
  
 0.998
RN09_2553
precorrin-6Y C(5,15)-methyltransferase; Overlaps another CDS with the same product name.
 
  
 0.985
CobB
Cobyrinic acid A,C-diamide synthase; Overlaps another CDS with the same product name.
 
 
 0.964
RN09_2550
precorrin-6A reductase.
 
   
 0.963
RN09_3453
Magnesium chelatase.
 
 
 0.956
RN09_1622
cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.938
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.931
CobI
Bifunctional S-adenosyl-L-methionine-precorrin-2 methyl transferase/precorrin-3 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.928
CobM
Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.905
CobU
Bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase.
 
   
 0.891
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.