Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2702Cytochrome c oxidase polypeptide 4; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. (139 aa)    
Predicted Functional Partners:
CtaE
Cytochrome C oxidase subunit III.
 
 0.999
CtaC
Cytochrome C oxidase subunit II.
 
 0.999
QcrB
Ubiquinol-cytochrome C reductase cytochrome subunit B.
 
 
 0.996
QcrA
Ubiquinol-cytochrome C reductase rieske iron-sulfur subunit.
 
 
 0.995
CtaD
Cytochrome C oxidase cytochrome 1; Overlaps another CDS with the same product name.
 
 0.995
QcrC
Ubiquinol-cytochrome C reductase cytochrome subunit C.
 
 
 
 0.994
RN09_3700
Cytochrome C oxidase cytochrome 1; Overlaps another CDS with the same product name.
 
 
 0.954
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
  
 0.952
RN09_1058
Hypothetical protein.
    
   0.948
RN09_3483
Transmembrane protein.
    
   0.939
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (8%) [HD]