Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LipMEsterase LipM. (290 aa)    
Predicted Functional Partners:
LipN
Lipase/esterase LipN.
  
   
 0.855
LipI
Lipase.
  
   
 0.781
RN09_2802
Diacylglycerol acyltransferase; Belongs to the long-chain O-acyltransferase family.
  
  
 0.732
LipW
Esterase LipW.
  
   
 0.674
FadD2
fatty-acid--CoA ligase FadD2.
  
 
 0.582
FadD12
long-chain-fatty-acid--CoA ligase FadD12.
  
 
 0.582
RN09_0384
Hypothetical protein.
 
   0.509
FadD8
fatty-acid--CoA ligase FadD8.
   
 
 0.461
RN09_3116
Transmembrane protein.
      
 0.456
AmiB2
Amidase AmiB2; Belongs to the amidase family.
    
 
 0.447
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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