STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RN09_2837Hypothetical protein. (198 aa)    
Predicted Functional Partners:
UvrD2
ATP-dependent DNA helicase UvrD.
  
 
 0.885
recC
Exonuclease V subunit gamma RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair [...]
  
 
 0.708
RN09_2836
Excisionase.
     
 0.703
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
  0.675
RecB
Exonuclease V subunit beta RecB; Overlaps another CDS with the same product name.
  
 
 0.631
RN09_0782
Exonuclease V subunit beta RecB; Overlaps another CDS with the same product name; Belongs to the helicase family. UvrD subfamily.
  
 
 0.631
RN09_2838
Hypothetical protein.
       0.614
RN09_2563
Hypothetical protein.
  
     0.605
RN09_1643
ATP-dependent helicase DinG.
   
 0.587
DinG
ATP-dependent helicase DinG.
   
 0.587
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.