Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CysK1O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)    
Predicted Functional Partners:
CysE
Serine acetyltransferase.
 
 0.999
MetB
Cystathionine gamma-synthase.
  
 0.975
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.972
NirA
Sulfite reductase; Overlaps another CDS with the same product name.
  
 
 0.947
CysK2
Cysteine synthase CysK.
  
  
0.929
RN09_4500
Lyase.
  
  
0.920
SerC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.910
RN09_0094
Aminotransferase; Overlaps another CDS with the same product name.
    
 0.909
RN09_2812
Cystathionine beta-lyase.
    
 0.909
RN09_0408
Dehydrogenase/reductase.
    
 0.906
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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