Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EsxO2ESAT-6 like protein EsxO; Belongs to the WXG100 family. (94 aa)    
Predicted Functional Partners:
EsxP2
ESAT-6 like protein EsxJ; Belongs to the WXG100 family.
       0.746
RN09_2891
Hypothetical protein.
     
 0.496
RN09_2892
PPE family protein PPE38; Belongs to the mycobacterial PPE family.
     
 0.496
RN09_2888
PPE family protein PPE38; Belongs to the mycobacterial PPE family.
     
 0.477
EsxA
ESAT-6 protein EsxA; Belongs to the WXG100 family.
   
  
 0.445
EsxB
ESAT-6-like protein EsxB.
   
  
 0.444
EsxL
ESAT-6 like protein EsxL; Belongs to the WXG100 family.
   
    0.418
CspA
Cold shock protein A.
  
    0.411
EsxG
ESAT-6 like protein EsxG; Belongs to the WXG100 family.
   
 
 0.405
PPE18
PPE family protein PPE18; Overlaps another CDS with the same product name; Belongs to the mycobacterial PPE family.
   
  
 0.405
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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