STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RN09_3109Hypothetical protein. (340 aa)    
Predicted Functional Partners:
UvrD2
ATP-dependent DNA helicase UvrD.
   
 0.994
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 0.956
RN09_1996
DNA polymerase I; Overlaps another CDS with the same product name.
   
 0.940
PolA
DNA polymerase I; Overlaps another CDS with the same product name.
   
 0.940
RN09_1998
DNA polymerase I; Overlaps another CDS with the same product name.
   
 0.940
LprE
Lipoprotein LprE.
   
 0.935
RN09_0796
50S ribosomal protein L1.
    
 0.837
RplA
50S ribosomal protein L1; Belongs to the universal ribosomal protein uL1 family.
    
 0.837
RN09_2572
5'-3' exonuclease.
   
 0.822
RN09_3328
Recombinase A.
   
 0.801
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.