Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LppALipoprotein LppA. (223 aa)    
Predicted Functional Partners:
LppB
Lipoprotein LppB.
  
    0.747
vapC-18
Ribonuclease VapC12; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
      
 0.590
PPE59
PPE family protein PPE59; Belongs to the mycobacterial PPE family.
      
 0.531
FadE32
acyl-CoA dehydrogenase FadE32.
      
 0.530
RN09_3123
Hypothetical protein.
       0.461
RN09_3122
Hypothetical protein.
       0.430
AroG
Phospho-2-dehydro-3-deoxyheptonate aldolase AroG; Belongs to the class-II DAHP synthase family.
      
 0.411
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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