Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_3286Hypothetical protein. (259 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
       0.777
RN09_3288
Alanine-rich transmembrane protein.
 
     0.775
RN09_3204
threonine--tRNA ligase.
  
     0.733
rbpA
RNA polymerase-binding protein RbpA; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.716
RN09_2964
Hypothetical protein.
  
     0.703
RN09_3298
Hypothetical protein.
  
     0.683
RN09_2255
HTH-type transcriptional regulator.
  
     0.661
SecG
Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.650
RN09_0990
Hypothetical protein.
  
     0.648
RN09_3877
Hypothetical protein.
  
   
 0.642
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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