sigA protein (Mycobacterium tuberculosis variant africanum)

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sigA

RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (528 aa)

Predicted Functional Partners:

rpoB

0.992

rpoC

0.985

rpoA

0.983

rbpA

0.982

rpoZ

0.956

RN09_4393

0.956

whiB-3

0.934

PhoP

0.907

whiB-2

0.901

RN09_2577

0.881

Your Current Organism:

Mycobacterium tuberculosis variant africanum

NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PhoP	rpoA	RN09_0935	RN09_4229	Two component system response transcriptional positive regulator PhoP.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.905
PhoP	rpoB	RN09_0935	RN09_0829	Two component system response transcriptional positive regulator PhoP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.909
PhoP	rpoC	RN09_0935	RN09_0830	Two component system response transcriptional positive regulator PhoP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.906
PhoP	rpoZ	RN09_0935	RN09_1710	Two component system response transcriptional positive regulator PhoP.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.808
PhoP	sigA	RN09_0935	RN09_3293	Two component system response transcriptional positive regulator PhoP.	RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.907
PhoP	whiB-3	RN09_0935	RN09_3913	Two component system response transcriptional positive regulator PhoP.	Transcriptional regulator WhiB1; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.761
RN09_2577	rbpA	RN09_2577	RN09_2527	Proteasome accessory factor C.	RNA polymerase-binding protein RbpA; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	0.836
RN09_2577	rpoA	RN09_2577	RN09_4229	Proteasome accessory factor C.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.783
RN09_2577	rpoB	RN09_2577	RN09_0829	Proteasome accessory factor C.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.891
RN09_2577	rpoC	RN09_2577	RN09_0830	Proteasome accessory factor C.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.795
RN09_2577	rpoZ	RN09_2577	RN09_1710	Proteasome accessory factor C.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.813
RN09_2577	sigA	RN09_2577	RN09_3293	Proteasome accessory factor C.	RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.881
RN09_4393	rbpA	RN09_4393	RN09_2527	RNA polymerase-binding transcription factor CarD.	RNA polymerase-binding protein RbpA; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	0.981
RN09_4393	rpoA	RN09_4393	RN09_4229	RNA polymerase-binding transcription factor CarD.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.957
RN09_4393	rpoB	RN09_4393	RN09_0829	RNA polymerase-binding transcription factor CarD.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
RN09_4393	rpoC	RN09_4393	RN09_0830	RNA polymerase-binding transcription factor CarD.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.965
RN09_4393	rpoZ	RN09_4393	RN09_1710	RNA polymerase-binding transcription factor CarD.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.964
RN09_4393	sigA	RN09_4393	RN09_3293	RNA polymerase-binding transcription factor CarD.	RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.956
RN09_4393	whiB-2	RN09_4393	RN09_3881	RNA polymerase-binding transcription factor CarD.	Transcriptional regulator WhiB7; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.813
rbpA	RN09_2577	RN09_2527	RN09_2577	RNA polymerase-binding protein RbpA; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	Proteasome accessory factor C.	0.836

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