Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_3306Hypothetical protein. (228 aa)    
Predicted Functional Partners:
RN09_3305
Hydrolase.
  
    0.810
RN09_3304
Alanine/leucine-rich protein.
       0.740
GltB
Glutamate synthase large subunit.
     
 0.520
RN09_0259
Hypothetical protein.
 
     0.458
RN09_4176
anti-sigma-D factor RsdA.
  
     0.449
RN09_0500
Membrane bound polyketide synthase.
 
  
 0.435
RN09_0276
Membrane protein.
  
     0.422
RN09_1112
Hypothetical protein.
  
     0.409
RN09_4061
Hypothetical protein.
  
     0.408
sthA
Pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.407
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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