Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FtsKDNA translocase FtsK; Overlaps another CDS with the same product name; Belongs to the FtsK/SpoIIIE/SftA family. (639 aa)    
Predicted Functional Partners:
RN09_3341
DNA translocase FtsK; Overlaps another CDS with the same product name.
      0.976
ParB
Chromosome partitioning protein ParB; Belongs to the ParB family.
  
  
 0.836
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
   
 
 0.794
xerC
Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.712
xerD
Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.706
PbpB
Penicillin-binding membrane protein PbpB.
 
 
 0.704
FtsW
Lipid II flippase FtsW; Belongs to the SEDS family.
 
  
 0.686
NusG
Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.
 
    0.665
ParA
Chromosome partitioning protein ParA.
  
  
 0.662
RN09_2101
Initiation inhibitor protein.
  
  
 0.625
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (20%) [HD]