Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RN09_3353Type I restriction/modification system specificity determinant HsdS; Overlaps another CDS with the same product name. (71 aa)    
Predicted Functional Partners:
HsdM
Type I restriction/modification system DNA methylase HsdM.
  
 
 0.986
HsdS
Type I restriction/modification system specificity determinant HsdS; Overlaps another CDS with the same product name.
      0.910
vapC-32
Ribonuclease VapC42; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.791
RN09_3352
Antitoxin VapB42.
       0.791
vapC-31
Ribonuclease VapC21; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.714
RN09_3350
Antitoxin VapB21.
       0.714
atpF
ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
   
 
 0.417
atpF-2
ATP synthase subunit b/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.
   
 
 0.417
RN09_1996
DNA polymerase I; Overlaps another CDS with the same product name.
   
 
 0.411
PolA
DNA polymerase I; Overlaps another CDS with the same product name.
   
 
 0.411
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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