Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPE44PPE family protein PPE44; Belongs to the mycobacterial PPE family. (368 aa)    
Predicted Functional Partners:
PE8
PE family protein PE27.
   
   0.809
RN09_2209
Hypothetical protein.
    
   0.795
RN09_2865
Hypothetical protein.
      
 0.667
PPE34
PPE family protein PPE34.
      
 0.660
PPE37
PPE family protein PPE37; Overlaps another CDS with the same product name.
      
 0.653
PE_PGRS16
PE-PGRS family protein PE_PGRS16.
      
 0.590
PE11
Lipase LipX.
      
 0.590
PE18
PE family protein.
      
 0.570
PE31
PE family protein PE31.
      
 0.518
PE_PGRS26
PE-PGRS family protein PE_PGRS2.
      
 0.511
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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