RN09_3496 protein (Mycobacterium tuberculosis variant africanum)

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Score

RN09_3496

Amidase AmiC; Overlaps another CDS with the same product name. (54 aa)

Predicted Functional Partners:

AmiC

0.800

gatC

0.763

gatB

0.743

aspS

0.595

atpF-2

0.474

pyrB

0.474

gltX

0.467

GuaA

0.464

pyrR

0.455

PyrF

0.454

Your Current Organism:

Mycobacterium tuberculosis variant africanum

NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AmiC	GuaA	RN09_3497	RN09_4153	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	GMP synthase.	0.464
AmiC	PyrF	RN09_3497	RN09_1705	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	0.454
AmiC	RN09_3496	RN09_3497	RN09_3496	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	Amidase AmiC; Overlaps another CDS with the same product name.	0.800
AmiC	aspS	RN09_3497	RN09_3157	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.595
AmiC	atpF-2	RN09_3497	RN09_1614	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	ATP synthase subunit b/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.	0.474
AmiC	gatB	RN09_3497	RN09_3656	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.	0.934
AmiC	gatC	RN09_3497	RN09_3661	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	glutamyl-tRNA(GLN) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.	0.821
AmiC	gltX	RN09_3497	RN09_3635	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.	0.467
AmiC	pyrB	RN09_3497	RN09_1700	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.474
AmiC	pyrR	RN09_3497	RN09_1699	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	Bifunctional pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.	0.455
GuaA	AmiC	RN09_4153	RN09_3497	GMP synthase.	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	0.464
GuaA	PyrF	RN09_4153	RN09_1705	GMP synthase.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	0.840
GuaA	RN09_3496	RN09_4153	RN09_3496	GMP synthase.	Amidase AmiC; Overlaps another CDS with the same product name.	0.464
GuaA	aspS	RN09_4153	RN09_3157	GMP synthase.	aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	0.884
GuaA	atpF-2	RN09_4153	RN09_1614	GMP synthase.	ATP synthase subunit b/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.	0.691
GuaA	gatB	RN09_4153	RN09_3656	GMP synthase.	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.	0.896
GuaA	gltX	RN09_4153	RN09_3635	GMP synthase.	glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.	0.826
GuaA	pyrB	RN09_4153	RN09_1700	GMP synthase.	Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.782
GuaA	pyrR	RN09_4153	RN09_1699	GMP synthase.	Bifunctional pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.	0.595
PyrF	AmiC	RN09_1705	RN09_3497	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.	0.454