Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PknISerine/threonine-protein kinase PknI. (256 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.696
RN09_3525
TetR family HTH-type transcriptional regulator.
     
 0.564
PknG
Serine/threonine-protein kinase PknG.
      
 0.553
RN09_3526
D-amino acid aminohydrolase; Overlaps another CDS with the same product name.
       0.530
RN09_3527
D-amino acid aminohydrolase; Overlaps another CDS with the same product name.
       0.530
PknF
Serine/threonine-protein kinase PknF.
 
    
 0.459
PknB
Serine/threonine-protein kinase PknB.
  
 
 0.454
RN09_2147
Serine/threonine-protein kinase PknF.
 
      0.435
Ppp
Phosphoserine/threonine phosphatase PstP.
  
 
 0.433
TB39.8
FHA domain-containing protein FhaA.
   
 
 0.433
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.