Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AcyPAcylphosphatase. (93 aa)    
Predicted Functional Partners:
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.946
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.918
RN09_0184
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.906
RN09_0565
Aldehyde dehydrogenase; Overlaps another CDS with the same product name; Belongs to the aldehyde dehydrogenase family.
    
 0.906
AldA
Aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family.
    
 0.906
acsA
acetyl-CoAsynthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.905
AmiB2
Amidase AmiB2; Belongs to the amidase family.
    
  0.903
AmiA2
Amidase; Overlaps another CDS with the same product name; Belongs to the amidase family.
    
  0.903
AmiC
Amidase AmiC; Overlaps another CDS with the same product name; Belongs to the amidase family.
    
  0.903
RN09_3858
Amidase.
    
  0.903
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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