Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DrrADaunorubicin ABC transporter ATP-binding protein DrrA. (281 aa)    
Predicted Functional Partners:
DrrC
Daunorubicin ABC transporter permease DrrC.
 
  
 0.994
DrrB
Daunorubicin ABC transporter permease DrrB.
  
  
 0.977
RN09_3564
Daunorubicin ABC transporter permease DrrB.
 
  
 0.965
PapA5
Phthiocerol/phthiodiolone dimycocerosyl transferase.
  
  
 0.940
RN09_1501
Tetronasin ABC transporter ATP-binding protein.
 
    
0.923
cysA
Sulfate ABC transporter ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
    
0.903
PpsE
Phthiocerol synthesis polyketide synthase type I PpsE.
  
 
 0.865
RN09_1500
Tetronasin ABC transporter integral membrane protein.
 
 
 0.859
PpsD
Phthiocerol synthesis polyketide synthase type I PpsD; Overlaps another CDS with the same product name.
  
 
 0.813
RN09_3560
Phthiocerol synthesis polyketide synthase type I PpsD; Overlaps another CDS with the same product name.
  
 
 0.797
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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