Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
AdhCNADP-dependent alcohol dehydrogenase. (239 aa)    
Predicted Functional Partners:
RN09_3703
NADP-dependent alcohol dehydrogenase.
     0.992
RN09_0184
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.925
RN09_0565
Aldehyde dehydrogenase; Overlaps another CDS with the same product name; Belongs to the aldehyde dehydrogenase family.
  
 0.923
AldA
Aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family.
  
 0.921
RN09_4337
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
     
 0.906
RN09_0226
Lysophospholipase.
     
  0.900
RN09_2080
Phosphatase.
     
  0.900
FecB
FeIII-dicitrate-binding periplasmic lipoprotein.
  
    0.610
AdhB
Alcohol dehydrogenase B.
  
 
 
0.547
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.540
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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