Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4012NAD(P)H quinone reductase LpdA; Overlaps another CDS with the same product name. (212 aa)    
Predicted Functional Partners:
RN09_4013
NAD(P)H quinone reductase LpdA; Overlaps another CDS with the same product name.
     0.994
SucA
Putative 2-oxoglutarate dehydrogenase SUCA (alpha-ketoglutarate dehydrogenase); Multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase.
  
 0.989
PdhC
Branched-chain keto acid dehydrogenase E2 component.
 
 0.922
SucB
Pyruvate dehydrogenase E2 component dihydrolipoamide acyltransferase.
 
 0.910
PdhB
Branched-chain keto acid dehydrogenase E1 component subunit beta.
 
 0.907
RN09_2721
Pyruvate dehydrogenase E2 component dihydrolipoamide acyltransferase; Overlaps another CDS with the same product name.
 
 0.871
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.833
GlpD2
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.827
PdhA
Branched-chain keto acid dehydrogenase E1 component subunit alpha.
 
 
 0.822
RN09_1034
Dehydrogenase.
 
 
 0.810
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (38%) [HD]