Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vapC-37Ribonuclease VapC44; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (142 aa)    
Predicted Functional Partners:
RN09_4037
Antitoxin VapB44.
  
    0.888
RN09_4038
Methyltransferase.
       0.790
MoaX
MoaD-MoaE fusion protein MoaX.
       0.790
MycP4
Membrane-anchored mycosin; Belongs to the peptidase S8 family.
      
 0.590
EsxE
ESAT-6 like protein EsxE; Belongs to the WXG100 family.
      
 0.590
ProX
Glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding lipoprotein ProX.
      
 0.576
mshA
D-inositol 3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
      
 0.571
vapC-19
Ribonuclease VapC13; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
   
 0.536
RN09_2485
Hypothetical protein.
  
     0.495
vapC-3
Ribonuclease VapC24; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
   
 0.472
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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