Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SigJECF RNA polymerase sigma factor SigJ; Belongs to the sigma-70 factor family. (315 aa)    
Predicted Functional Partners:
RN09_2121
Hypothetical protein.
  
    0.812
RN09_4051
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.775
SirR
Transcriptional repressor SirR.
  
    0.774
RN09_0465
HTH-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
  
 0.772
RN09_2388
Transcriptional regulator.
  
  
 0.771
RN09_4565
AraC/XylS family transcriptional regulator.
   
  
 0.771
RN09_2185
Transcriptional regulator.
   
  
 0.769
RN09_3352
Antitoxin VapB42.
   
    0.761
RN09_3966
DNA methylase.
   
    0.761
SigL
ECF RNA polymerase sigma factor SigL; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.760
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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