Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DacB1Penicillin-binding protein DacB; Belongs to the peptidase S11 family. (405 aa)    
Predicted Functional Partners:
PbpB
Penicillin-binding membrane protein PbpB.
 
 
 0.974
PbpA
Penicillin-binding protein PbpA.
 
 
 0.970
RN09_4439
Hypothetical protein.
     
 0.967
DacB2
Penicillin-binding protein DacB2; Belongs to the peptidase S11 family.
  
  
 
0.910
RN09_4051
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.693
PonA1
Bifunctional penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase.
 
  
 0.660
NagA
N-acetylglucosamine-6-phosphate deacetylase NagA.
     
 0.657
RN09_3471
Penicillin-binding lipoprotein.
 
  
 0.619
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.565
SugI
Sugar-transport integral membrane protein SugI; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
     
 0.564
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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