Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PhyAPhytoene synthase. (302 aa)    
Predicted Functional Partners:
IdsA1
Multifunctional dimethylallyltransferase/geranyltranstransferase/farnesyl transtransferase; Belongs to the FPP/GGPP synthase family.
 
 0.990
IdsA2
Geranylgeranyl pyrophosphate synthetase IdsA; Belongs to the FPP/GGPP synthase family.
  
 0.953
IdsB
Polyprenyl synthetase IdsB; Overlaps another CDS with the same product name.
  
 0.903
Gap
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.808
RN09_4157
S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
 
    0.793
Erg3
Membrane-bound C-5 sterol desaturase.
  
 
 0.785
RN09_0501
Membrane bound polyketide synthase; Overlaps another CDS with the same product name.
  
 0.778
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.746
RpsA
30S ribosomal protein S1.
   
    0.721
RN09_0500
Membrane bound polyketide synthase.
  
 0.701
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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