Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4166HTH-type transcriptional regulator. (188 aa)    
Predicted Functional Partners:
RN09_4167
Dioxygenase.
     
 0.922
cobB
NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily.
   
  
 0.763
RN09_4158
Hydrolase.
      
 0.672
RN09_0259
Hypothetical protein.
  
     0.667
RN09_3274
Antibiotic ABC transporter permease.
 
     0.637
RN09_4165
Hypothetical protein.
       0.624
RN09_3275
Antibiotic ABC transporter permease.
 
     0.614
RN09_4565
AraC/XylS family transcriptional regulator.
  
  
 0.613
RN09_2799
LysR family HTH-type transcriptional regulator.
   
 
 0.587
RN09_3866
Transcriptional regulator.
   
    0.567
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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