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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
RN09_4243Acetolactate synthase large subunit. (190 aa)    
Predicted Functional Partners:
IlvB2
Acetolactate synthase large subunit; Overlaps another CDS with the same product name.
   
 0.949
IlvN
Acetolactate synthase small subunit.
 
 
 0.918
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.874
RN09_4242
Acetolactate synthase large subunit; Overlaps another CDS with the same product name.
 
   
 0.868
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.863
IlvG
Acetolactate synthase large subunit IlvG.
  
  
  0.837
MhpE
4-hydroxy-2-oxovalerate aldolase MhpE.
 
 
 0.784
RN09_4244
Hypothetical protein.
  
    0.776
IlvB1
Acetolactate synthase large subunit IlvB.
  
  
 
0.659
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.653
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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