Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
OtsATrehalose-phosphate synthase. (314 aa)    
Predicted Functional Partners:
OtsB2
Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.999
RN09_4265
Hypothetical protein.
     0.990
GalU
UTP--glucose-1-phosphate uridylyltransferase.
    
 0.951
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
    
 0.934
RN09_3687
Glycogen synthase.
    
 0.911
RN09_4263
Hypothetical protein.
       0.872
RN09_2952
Trehalase; Overlaps another CDS with the same product name.
 
   
 0.837
TreS
Trehalose synthase/amylase TreS.
 
  
 0.833
TreY
Maltooligosyl trehalose synthase.
  
  
 0.825
RN09_2951
Trehalase; Overlaps another CDS with the same product name.
 
   
 0.823
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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