Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EchA20enoyl-CoA hydratase EchA20. (247 aa)    
Predicted Functional Partners:
RN09_4353
CoA-transferase subunit alpha.
 
 
 0.999
RN09_4354
CoA-transferase subunit beta.
 
 0.999
RN09_4355
Oxidoreductase.
 
 
 0.996
RN09_4362
Oxidoreductase.
 
 0.981
RN09_4351
Short-chain type dehydrogenase/reductase.
 
 0.976
RN09_4350
Short-chain type dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.951
FadE30
acyl-CoA dehydrogenase FadE30.
 
 0.951
FadE29
acyl-CoA dehydrogenase FadE29.
 
 0.927
RN09_4368
acyl-CoA dehydrogenase FadE32.
 
 0.918
FadD3
fatty-acid--CoA ligase FadD3.
 
 
 0.910
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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