Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4397DNA integrity scanning protein DisA; Belongs to the DisA family. (386 aa)    
Predicted Functional Partners:
RadA
DNA repair protein RadA; Overlaps another CDS with the same product name.
  
  
 0.967
RN09_4396
DNA repair protein RadA; Overlaps another CDS with the same product name.
  
  
 0.967
LpqE
Lipoprotein LpqE.
     
 0.762
RN09_3439
Bifunctional oligoribonuclease/PAP phosphatase NrnA.
  
   
 0.731
RN09_2918
Hypothetical protein.
  
     0.719
RN09_3500
Hypothetical protein.
     
 0.681
RN09_4625
Hypothetical protein.
     
 0.681
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
    0.634
RN09_4538
Hypothetical protein.
  
    0.602
RN09_3891
ATP-dependent DNA helicase; Overlaps another CDS with the same product name; Belongs to the helicase family. UvrD subfamily.
   
    0.554
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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