Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LpqFLipoprotein LpqF. (438 aa)    
Predicted Functional Partners:
TB11.2
Heme-degrading monooxygenase.
     
 0.945
RN09_4407
Hydrolase.
       0.759
RN09_3335
Transmembrane alanine-rich protein.
  
     0.747
RN09_4530
Hypothetical protein.
  
     0.743
RN09_0357
Transmembrane protein.
  
     0.741
RN09_1001
Exported protein.
  
     0.725
InfC
Initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
     
 0.679
ThiS
Sulfur carrier protein ThiS.
  
     0.665
RN09_1795
Hypothetical protein.
  
     0.602
LprC
Lipoprotein LprC.
 
     0.583
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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