| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FolB | FolK | RN09_4425 | RN09_4424 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.999 |
| FolB | FolP1 | RN09_4425 | RN09_4426 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| FolB | RN09_4423 | RN09_4425 | RN09_4423 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Secreted protein. | 0.872 |
| FolB | RN09_4429 | RN09_4425 | RN09_4429 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein. | 0.496 |
| FolB | folE | RN09_4425 | RN09_4427 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I. | 0.996 |
| FolB | ftsH | RN09_4425 | RN09_4428 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.931 |
| FolK | FolB | RN09_4424 | RN09_4425 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| FolK | FolP1 | RN09_4424 | RN09_4426 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| FolK | RN09_4423 | RN09_4424 | RN09_4423 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Secreted protein. | 0.872 |
| FolK | RN09_4429 | RN09_4424 | RN09_4429 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Hypothetical protein. | 0.496 |
| FolK | folE | RN09_4424 | RN09_4427 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | GTP cyclohydrolase I. | 0.994 |
| FolK | ftsH | RN09_4424 | RN09_4428 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.802 |
| FolP1 | FolB | RN09_4426 | RN09_4425 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| FolP1 | FolK | RN09_4426 | RN09_4424 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.999 |
| FolP1 | RN09_4423 | RN09_4426 | RN09_4423 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Secreted protein. | 0.872 |
| FolP1 | RN09_4429 | RN09_4426 | RN09_4429 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein. | 0.496 |
| FolP1 | folE | RN09_4426 | RN09_4427 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I. | 0.996 |
| FolP1 | ftsH | RN09_4426 | RN09_4428 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.906 |
| RN09_4423 | FolB | RN09_4423 | RN09_4425 | Secreted protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.872 |
| RN09_4423 | FolK | RN09_4423 | RN09_4424 | Secreted protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.872 |