Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RN09_4433ESX-1 secretion-associated protein EspA. (401 aa)    
Predicted Functional Partners:
RN09_4432
ESX-1 secretion-associated protein EspC.
  
  
 0.975
RN09_4431
ESX-1 secretion-associated protein EspD.
  
  
 0.960
RN09_4743
ESX-1 secretion-associated protein EspB.
  
  
 0.802
EsxB
ESAT-6-like protein EsxB.
  
 
 0.751
EsxA
ESAT-6 protein EsxA; Belongs to the WXG100 family.
  
 
 0.708
RN09_4430
Hypothetical protein.
  
  
 0.705
RN09_4705
ESX-1 transcriptional regulator EspR.
      
 0.679
RN09_4725
ESX-1 secretion-associated protein EspH.
  
  
 0.652
PhoP
Two component system response transcriptional positive regulator PhoP.
   
  
 0.519
RN09_4723
ESX-1 secretion-associated protein EspG; Overlaps another CDS with the same product name.
  
  
 0.491
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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